ECTS
ECTS Course Catalogue
Course details
Course code: NBSS10124o13Semester: 2013/2014 summer
Name: Molecular Biology
Major: Biotechnology
Study Type: first cycle
Course type: compulsory
Study Semester: 6
ECTS points: 6
Hours (Lectures / Tutorials / Other): 45 / 30 / 0
Lecturer: dr hab. Małgorzata Robak
Language of instruction: Polish
Learning outcomes: After completing the course student have know mechanisms of molecular regulation of gene expression in prokaryote and eukaryote. Student understand restriction analyses and are capable to use basic internet data bases containing information about gene and protein.
Competences: Student is able to work with basic apparatus for genome and proteome analyses: protein and DNA electrophoresis sets (PAGE and sepharose system), thermocyclers (PCR), gel documentation , data bases and internet availble tools.
Prerequisites: Inorganic Chemistry, Cell Biology, Biochemistry, General Microbiology
Course content: Prokaryotic and eukaryotic cell organization. Proteome: protein structure, function , methods of analysis, proteasomic degradation. Genome : organization and methods of analysis, DNA structure, gene, intron, exons . RNA and transcriptom : structure, function. Metabolic molecular biology: DNA replication , gene organization, regulation of expression, regulation of transcription in Prokaryota and Eukaryota. Importance of RNA in the control of protein biosynthesis: rybosome organisation, tRNA, rRNA, hnRNA, splicing, rybozym. Protein degradation. Introduction to Bioinformatics.
Recommended literature: 1. Podstawy biologii komórki, Wprowadzenie do biologii molekularnej, Alberts i wsp.,PWN, Warszawa, 1999; 2. Zasady analizy genomu, Primrose S.B., WNT, Warszawa, 1999; 3. Biologia molekularna, Krótkie wykłady, turner i wsp., PWN, Warszawa, 2000; 4. Biofizyka kwasów nukleinowych dla biologów, Bryszewska i Leyko , PWN,Warszawa, 2000; 5. Genomy, Brown T., PWN, Warszawa, 2001; 6. Genes VIII, Lewin B., Pearson Prentice Hall, NY, 2004.
Assessment methods: Reports and written exam, minimum 60% of knowledge required to pass the course
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