Courses list

Wersja polska

Course code: BIS10045o14
Semester: 2014/2015 winter
Name: Genomics and Proteomics
Major: Bioinformatics
Study Type: first cycle
Course type: compulsory
Study Semester: 5
ECTS points: 4
Hours (Lectures / Tutorials / Other): 15 / 30 / 0
Lecturer: dr Bożena Marszałek-Kruk / dr Tomasz Strzała
Language of instruction: Polish / English
The course taught in English if the group has ≥6 students. The course taught in Polish with a possibility of support in English if the group has <6 students. Contact person: dr Tomasz Strzała

Learning outcomes: Knowledge: can compare and determine the difference between nuclear and mitochondrial genomes of different species of animals and plants [BI_W07, BI_W09, BI_W11, BI_W12, BI_W15, BI_W17]; knows the methods of mapping and sequencing genomes [BI_W04, BI_W11, BI_W12, BI_W15, BI_W17]; knows the structure and function of proteins in the cell, has a general knowledge of the techniques of protein identification [BI_W11, BI_W12, BI_W14, BI_W16, BI_W17]; knows the techniques of gel electrophoresis of proteins [BI_W04, BI_W07, BI_W08, BI_W09, BI_W11, BI_W12, BI_W14, BI_W15, BI_W16, BI_W17]; knows the concept of denaturation, proteome, etc. [BI_W08, BI_W11, BI_W12, BI_W16, BI_W17]. Skills can use the selected databases of genomic sequences [BI_U01, BI_U04, BI_U05, BI_U09, BI_U13, BI_U14]; can analyze the differences in the structure of simple genomes and determine the functions of the various elements that build them [BI_U03, BI_U04, BI_U05, BI_U07, BI_U11]; acquires the ability to prepare denaturing gel, can perform protein electrophoresis in denaturing conditions and in native methods [BI_U02, BI_U04, BI_U05, BI_U07]; gains skills of the relevant computer programs used to analyze the spatial structures of proteins [BI_U01, BI_U03, BI_U04, BI_U05, BI_U07, BI_U11, BI_U13, BI_U14].

Competences:

Prerequisites: biochemistry, genetics, molecular biology, basics of bioinformatics

Course content: Anatomy of the genomes, comparative analysis and phylogeny of the genomes, the functioning of genomes, the mechanisms of genome evolution, the construction of the human genome. Proteins and their functions in the cell; protein profiling, method for identification of proteins in proteome; Identification of proteins interacting with each other; relation and sequence of proteomics, metabolomics, biological systems

Recommended literature: 1. Brown T.A. Genomy, PWN Warszawa, 2009 2. Bergman, Nicholas H. Comparative Genomics, Humana Press, 2007 3. Drewa G., Ferenc T. Genetyka medyczna. Elsevier Urban & Partner, Wrocław 2011. 4. Passarge E.: Genetyka. Wyd. Lekarskie PZWL 2004. 5. Węgleński P. Genetyka molekularna. Wyd. Naukowe PWN, Warszawa 2006. 6. Connor M., Ferguson-Smith M. Podstawy genetyki medycznej. Wyd. Lekarskie PZWL: 1998. 7. Bal J. Biologia molekularna w medycynie. Wyd. Naukowe PWN, Warszawa 2007. 8. Epstein RJ. Biologia molekularna człowieka. Wydawnictwo Czelej 2005

Assessment methods:

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