ECTS
ECTS Course Catalogue
Course details
Course code: NBSS20236f14Semester: 2014/2015 winter
Name: Application of chiral catalysts in biotechnology, pharmacy
Major: Biotechnology
Study Type: second cycle
Course type: optional
Study Semester: 2
ECTS points: 1
Hours (Lectures / Tutorials / Other): 15 / 0 / 0
Lecturer: dr hab. Teresa Olejniczak
Language of instruction: Polish
Learning outcomes: Learning outcomes: Knowledge After the course the student is familiar with the various aspects of the application of chiral catalysts. Knows the use of enzymes, chiral catalysts in the synthesis of selected chiral pharmaceuticals. Skills On the basis of the application of chiral catalysts in modern biotechnology, pharmacy analyses methods used in scientific publications. Is able to find the catalyst to enantiselective synthesis of biologically active compounds.
Competences: Social skills (attitude) The student is creative, capable of solving problems presented during the lecture the scope of application of chiral catalysts. In the course of the discussion is active and open of the opinion of others, aware of the rapidly progressive development of the biological sciences.
Prerequisites: Organic Chemistry, Biochemistry
Course content: Structure of chiral catalysis. It mechanism of catalysts action. Catalysis overview in the example of reduction of ketones, double bonds, enantioselective epoxidation, dihydroxylation, esterification, hydrolysis of biologically active compounds.
Recommended literature: 1. David J. Ager, Handbook of chiral chemicals, Marcel Dekker, INC, New York, 1999 2. Garry Procter, Asymmetric synthesis, Oxford University Press, 1996 3. Cyntha A. Challener, Chiral intermediates, Ashgate Publishing Company 2001 4. Tetrahedron: Asymmetry-Elsevier- wybrane publikacje z lat 2009-2013 5. Peter Grunwald, Biocatalysis Imperial College Press 2009.
Assessment methods: Written final exam (test)
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