ECTS
ECTS Course Catalogue
Course details
Course code: BBS10143f10Semester: 2010/2011 winter
Name: Association analysis
Major: Biology
Study Type: first cycle
Course type: optional
Study Semester: 5
ECTS points: 3
Hours (Lectures / Tutorials / Other): 15 / 30 / 0
Lecturer: dr hab. prof. nadzw. Joanna Szyda
Language of instruction: Polish
Learning outcomes: Students obtain theoretical knowledge of genetic and biometrical basis of association analysis – detection of association between observed, phenotypical variation among individuals and genetic variation. Additionally, based on a real data set, the student learns how to perform the association analysis using computer programs as well as how to interpret results obtained.
Competences: The course allows students for independent choice of statistical methodology and for carrying statistical analysis of data obtained through the modern methods of molecular biology, which are currently widespread in human and animal genetics, such as SNP markers, microarrays, or DNA sequencing. The student will be able to work with large data sets.
Prerequisites: biometrics, genetics, mathematics
Course content: Linkage, association, linkage disequilibrium, association analysis, gene detection.
Recommended literature: Andrew R. Collins (2007) Linkage Disequilibrium and Association Mapping: Analysis and Applications (Methods in Molecular Biology), Humana Press; Krystyna Charon, Marek Świtoński (2006) Genetyka ogólna. PWN; PLINK http://pngu.mgh.harvard.edu/~purcell/plink/
Assessment methods: Completion of the practical training part is based on grades, which are granted during the semester (written class works, group projects); minimum 70% of knowledge to pass.
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