ECTS
ECTS Course Catalogue
Course details
Course code: NBSS10121f11Semester: 2011/2012 winter
Name: Industrial pharmaceutical biotechnology
Major: Biotechnology
Study Type: first cycle
Course type: optional
Study Semester: 5
ECTS points: 7
Hours (Lectures / Tutorials / Other): 30 / 60 / 0
Lecturer: dr hab. Małgorzata Robak, prof. nadzw., prof. dr hab. Danuta Witkowska,
Language of instruction: Polish
Learning outcomes: students understand biotechnological processes of: vitamins, antibiotics, vaccines, antibodies, dextrans and selected recombined biopharmaceutics production by defined strains of microorganisms and animals or vegetal cell lines carried out in different culture systems.
Competences: students are able to plan and supervise pharmaceutical biotechnological processes occurring with microorganism and cell lines.
Prerequisites: biochemistry, general microbiology
Course content: Biocatalysts utilized in biotechnological processes: microorganisms, animal and vegetal cells lines; their advantages and disadvantages ; improvement (mutagenisation, DNA recombination), storage. Environment and culture systems. Principles of bioprocess control and processes guidance. Overview of industrial synthesis of pharmacologically active compounds (antibiotics, vitamins, hormones, monoclonal antibodies, interferons, vaccines ). Basis of formulation of medicaments obtained by biotechnological methods. Law and social aspects of pharmaceutical biotechnology.
Recommended literature: 1.Biotechnologia farmaceutyczna, praca zbiorowa pod redakcją R. H. Muller i O. Kayser, PZWL, 2003; 2.Podstawy Biotechnologii farmaceutycznej, O. Kayser, Wydawnictwo Uniwersytetu Jagiellońskiego, 2006; 3.Biotechnologia: podstawy mikrobiologiczne i biochemiczne, A. Chmiel, Wydawnictwo naukowe PWN, 1998, 4.Biotechnologia i chemia antybiotyków, A. Chmiel, S. Grudziński, Wydawnictwo Naukowe PWN, 1998; 5.Biotechnologia zwierząt, praca zbiorowa pod redakcją L. Zwierzchowskiego, K. Jaszczaka, J.A Modlińskiego, Wydawnictwo naukowe PWN, 1997; 6.Biotechnologia roślin, praca zbiorowa pod redakcją S. Maleszy, Wydawnictwo naukowe PWN, 2005; 7.Podstawy wybranych procesów biotechnologicznych, praca zbiorowa pod redakcją Jana Fiedurka, Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, Lublin 2004. 8. Pharmaceutical biotechnology. Fundamentals and applications. Edited by Daan J.A. Crommelin, Robert D.Sindelar, Bernd Meibohm. Wydawnictwo: informa healthcare, New York, London 2008
Assessment methods: written exam, minimal required knowledge- 60%
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