ECTS
ECTS Course Catalogue

Course details
Course code: NBSS10135f15
Semester: 2015/2016 winter
Name: Laboratory animals and their use in biotechnology
Major: Biotechnology
Study Type: first cycle
Course type: optional
Study Semester: 7
ECTS points: 2
Hours (Lectures / Tutorials / Other): 12 / 12 / 0
Lecturer: dr hab. Anna Chełmońska-Soyta
Language of instruction: Polish


Learning outcomes: Knowledge: student after finishing the course: -describes the goals and methods of working with laboratory animals, -lists the rights of laboratory animals and ethical requirements of working with these animals, -describes the sanitary requirements and principles of laboratory animal husbandry, - covers the basics of anatomy and physiology, genetic diversity and related methods of genetic modification of laboratory animals -explains the rules of experiments on laboratory animals -proposing alternative methods which do not require working with live animals Skills: - draws up a proposal to the ethics committee for permission to conduct experiments with laboratory animals - submits a draft of the experiment with laboratory animals

Competences: Student consciously and responsibly decides on the use of laboratory animals for experimental purposes

Prerequisites: Biochemistry, Genetics, Immunology

Course content: Basic knowledge in ethics and legislation of the use of animals in biomedical research, anatomy, physiology, reproduction and behavior of laboratory animals, biochemical and hematological markers in healthy animals, animal facilities- organization and hygiene, breeding and feed regiment, genetic diversity in mice and rats, transgenesis, transgenic animals and gene knockouts animals, examination of gene expression in vivo and ex vivo, immunological, pharmacological and toxicological tests and experiments designing, low vertebrates and non-vertebrates as laboratory animals, screening test “omics” type, cell and tissue culture as an alternative methods of experiments

Recommended literature: 1. „Zwierzęta Laboratoryjne, Metody Hodowli i Doświadczeń” – Jadwiga Brylińska, Janina Kwiatkowska wyd. Universitas, 1996. 2. Genetyka molekularna , P.Węgliński, PWN,2007 3. Ssaki transgeniczne, Bishop J, PWN,2001 4. Handouts from lecures and seminars ( EDUWET ) platform

Assessment methods: written partial exams, project assesement

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